In , 1 cases of Lymphogranuloma venereum (LGV) were reported in 23 countries. M. Vall-Mayans, I. NoguerBrotes de linfogranuloma venéreo entre hombres homosexuales en Europa, Enferm Infecc Microbiol Clin, 24 (), pp. Request PDF on ResearchGate | Linfogranuloma venéreo: una causa emergente de proctitis en hombres homosexuales en Barcelona | Background and.

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Some authors suggest that the increase of cases reported in recent decades is due to the development of diagnostic tests for serotypes L1, L2 and L3 of Chlamydia sincewhich have emerged these infections previously undiagnosed. The exclusion of squamous cell carcinoma in patient 1 was of prime importance for the patient Figure 2.

The diagnosis is often made serologically and by exclusion of other causes of inguinal lymphadenopathy or genital ulcers. An year-old male had a two-month history of a progressively indurating papule of the gland penis, followed by ulceration. Sexually Transmitted Disease Chapter. Gastroenterologists are beholden to suspect this emerging disease when compatible symptoms are present, especially in MSM, and not ignore an endoscopic examination and mistaken this disease with trivial anal problems.

After a detailed analysis of all the bibliographic sources, we cannot entirely exclude the hypothesis that histopathological findings in LGV-patients can also evolve, in concert with the clinicopathologic findings.

Lymphogranuloma venereum: “a clinical and histopathological chameleon?”

Other alternatives are erythromycin mg orally four times daily for 3 weeks or a single oral dose cenereo azithromycin 1 g once weekly for 3 weeks. Histopathological findings A bone marrow biopsy showed plasma cells and gammopathy of uncertain significance. It also focuses on alternative therapeutic approaches, such as surgical excision at stage 1, that may lead to a positive limfogranuloma.


The mean age was As a supporting procedure, extirpation of single lymphatic nodes from the submandibular area was performed, and histopathological findings were identical.

Response to antibiotic treatment is usually complete after 3 or 6 weeks and all lesions disappear in most venedeo. Differential Diagnosis Inflammatory Bowel Disease. All cases were confirmed by polymerase chain reaction technique in rectal tissue. In the reappearance of this disease its presentation has changed and, today, proctitis is the most common initial clinical manifestation.

Back Links pages that link to this page. Pyoderma gangrenosum in Crohn’s disease – The role of immunologic parameters and histological data in diagnosis and differential diagnosis.

Case detection and study of contacts to prevent the spread of the disease is a challenge for all health professionals. The epidermis showed hyperkeratosis, with both ortho- and parakeratosis. Approved by the Advisory Board and accepted for publication on The positive serology with respect to Chlamydia trachomatis and the rapid response to antimicrobial therapy indisputably lead to the interpretation of a rare form of LGV infection.

Rectal lymphogranuloma venereum surveillance in France Lymphogranuloma venereum proctosigmoiditis is a mimicker of inflammatory bowel disease.

Lymphogranuloma venereum

How to cite this article. It is assumed that each stage of LGV has a different clinical and histopathological morphology. Related Bing Images Extra: Up to now, and in our knowledge, there has been no reported case of endoscopic dilation in anal strictures, although it could be an alternative procedure to consider.

Related links to external sites from Bing. After a mean follow up of A Chlamydia smear from the urethra was also negative. The critically increased values of IgM serology do not eliminate the possibility of a localized, superinfected, macerated, genital form of varicella-zoster viral infection.


We present five cases of LGV proctitis as the initial presentation of the disease. Immunohistochemically, there was evidence of a chronic histiocytic macrophagic and fibrosing balanitis.

Lymphogranuloma venereum in the United kingdom. Lymphogranuloma venereum is an infection caused by a variety of the bacterium Chlamydia trachomatis. Linfogrqnuloma question of whether histopathological findings in this LGV-suffering patient could evolve to an image similar to that of other granulomatous diseases, such as pyoderma gangrenosum, remains unanswered.

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Mabey D, Peeling RW. Results from contact tracing and public health implications. His history was positive for internal diseases, including a positive serology for rheumatoid arthritis, diabetes mellitus type II, glaucoma, heart failure status after bypass interventionand hypertension. An initial consideration of skin cancer is not unreasonable in patients such as those discussed above, since clinical findings can be linfogfanuloma similar and histopathology is not always conclusive.

IgG positive – 4. The first case in Spain was reported in in Barcelona 1. We do not exclude the possibility that an ulcerating balanitis could be generated within the context of seropositive, active rheumatoid arthritis, which is frequently able to initiate nonspecific skin and mucosal ulcerations.


According to the New York State Department of Health, the incidence of lymphogranuloma venereum LGV is highest among sexually active people living in tropical or subtropical climates, including some areas in the southern U. Search other sites for ‘Lymphogranuloma venereum’.