There is a direct relationship between the lack of estrogen after menopause and . Getting enough calcium throughout your life helps to build and keep strong. Osteoporotic women have decreased calcium absorption and decreased serum Estrogen therapy improves calcium balance in patients with postmenopausal. Understanding the Calcium Connection [Constant exchange mechanism between bone calcium and blood serum calcium]; The Role of Estrogen [ Estrogen.
The objective was to investigate the importance of the source of calcium intake on estrogen metabolism and BMD.
The average total daily calcium intake from supplements and diet, urinary estrogen metabolites, and spine and proximal femur BMD were studied in healthy postmenopausal white women. This difference was evident especially in those who obtained calcium primarily from the diet, whose total calcium intake was lower than that in those who obtained calcium primarily from supplements.
On the other hand, the same group of women are protected from bone loss and osteoporosis, presumably by the same underlying mechanism 810whereas the opposite is true when the 2-hydroxyl pathway predominates. These findings suggest that the manipulation of these pathways may alter the risk of certain hormone-dependent conditions. There are several factors that modulate estrogen metabolism.
Smoking 11 and high consumption of indole-containing vegetables 12 have been found to enhance 2-hydroxylation of estrogen. Medications such as cimetidine may inhibit estrogen hydroxylation 13whereas thyroid hormones increase 2-hydroxylation Very recently, we have added calcium to the list of agents that may influence estrogen metabolism by demonstrating that increasing calcium intakes are associated with increasing concentrations of estrogen metabolites However, as we pointed out in that report, the significantly positive correlation between calcium intake and urinary metabolites was mainly observed in subjects whose calcium intake came from dietary sources.
Meanwhile, the effect of different calcium sources on modulating estrogen hydroxylation and their consequence on bone metabolism remains undetermined. Considering that there are a variety of calcium sources available, it is possible that a differential effect on estrogen metabolism between the different sources exists and this may have an effect on BMD.
The objective of this study, therefore, was to investigate the effect of the type of calcium intake on estrogen hydroxylation and bone density in a group of healthy postmenopausal women.
Participants were recruited through advertisements or direct mailing. This study was conducted in accordance with the guidelines in the Declaration of Helsinki for the appropriate treatment of human subjects. The protocol was approved by the Washington University School of Medicine Institutional Review Board, and written informed consent was obtained from each participant.
Menopause & Osteoporosis | Cleveland Clinic
Beyond reproductive functions, estrogen affects the bones, heart and cognitive function. Although often used in the singular, the term estrogen actually refers to a group of hormones, such as estradiol.
Understanding Calcium Calcium is one of the most important minerals in the body. The majority of it is found in your teeth and bones, but it is also involved in muscle function, blood clotting and nerve function. You can get a considerable amount of calcium from the foods you eat, particularly dairy products; nuts; fortified foods; and dark, leafy greens.
In some cases, however, your doctor may recommend a supplement to increase your calcium level.Calcium Homeostasis and Parathyroid Hormone - PTH
Having a low level puts you at risk for brittle bones and muscle problems. Maintaining an appropriate level of calcium is important not only for bone growth over time but also for protecting bone strength.
The BioCalcium supplement we carry has been specifically formulated to match this successful clinical study formulation. N Engl J Med ; Recker RR et al. Effect of estrogen and calcium carbonate on bone loss in postmenopausal women. Ann Intern Med Calcium in the prevention and management of osteoporosis.
Lee CJ 45 al. Effects of supplementation of the diet with calcium and calcium-rich foods on bone density of elderly females with osteoporosis. Am J Clin Nutr ; Riis B, et al. Does calcium supplementation prevent postmenopausal bone loss?
Albanese AA, et al. Effects of calcium and micronutrients on bone loss of pre and postmenopausal women. Gallagher, JC, et al.
Menopause & Osteoporosis
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The Relationship Between Estrogen & Calcium Levels
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